Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylamine SCHEMBL7578440 | 0.94 | HSD17B10 (0.52) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL6406231 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL175889 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL3428485 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL1173026 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL28999966 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL4614917 | 0.82 | MEN1 (0.44) | ALDH1A1ALOX12TSHRL3MBTL1ALOX15 | |
| SCHEMBL6608023 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL11138322 | 0.81 | CYP3A4 (0.58) | ALDH1A1HSD17B10ALOX12TSHRALOX15 | |
| SCHEMBL7757717 | 0.80 | ADRA2B (0.40) | ALDH1A1HSD17B10ALOX12TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969027-B1 | ARYLAMINE POLYMER | CAMBRIDGE DISPLAY TECH LTD (GB) | 2013-10-02 | — | — | EP | disclosed |
| US-8399761-B2 | Organic photovoltaic device with interfacial layer and method of fabricating same | NORTHWESTERN UNIVERSITY (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399605-B2 | Arylamine polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2013-03-19 | — | — | US | disclosed |
| WO-2011136800-A1 | ORGANIC PHOTOVOLTAIC DEVICE WITH INTERFACIAL LAYER AND METHOD OF FABRICATING SAME | NORTHWESTERN UNIVERSITY (US) | 2011-11-03 | — | — | WO | disclosed |
| US-20100252113-A1 | ORGANIC PHOTOVOLTAIC DEVICE WITH INTERFACIAL LAYER AND METHOD OF FABRICATING SAME | NORTHWESTERN UNIVERSITY (US) | 2010-10-07 | — | — | US | disclosed |
| US-20080309229-A1 | Arylamine Polymer | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080309229-A1 | Arylamine Polymer | NAT1, AR, AHR | ALDH1A1 627/4885HSD17B10 1121/4885ALOX12 3225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.