Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OGT | O15294 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491863 | 0.88 | NOS1 (0.53) | NOS1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8786452 | 0.85 | NOS1 (0.49) | NOS1ALDH1A1IL4I1CREBBPKDM4E | |
| SCHEMBL7408427 | 0.85 | NOS1 (0.49) | NOS1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5536087 | 0.85 | NOS1 (0.49) | NOS1ALDH1A1IL4I1CREBBPKDM4E | |
| SCHEMBL4891443 | 0.85 | KDM4E (0.51) | NOS1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5536042 | 0.84 | NOS1 (0.47) | NOS1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL10392913 | 0.83 | NOS1 (0.50) | NOS1ALDH1A1IL4I1CREBBPKDM4E | |
| SCHEMBL4675522 | 0.83 | KDM4E (0.52) | NOS1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5535563 | 0.83 | NOS1 (0.50) | NOS1ALDH1A1IL4I1CREBBPKDM4E | |
| SCHEMBL9463816 | 0.83 | NOS1 (0.48) | NOS1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998741-B1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2012-03-07 | — | — | EP | disclosed |
| EP-1998741-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2008-12-10 | — | — | EP | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| WO-2007112854-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2007-10-11 | — | — | WO | disclosed |
| US-20070231282-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | CONOPCO, INC., D/B/A UNILEVER | 2007-10-04 | — | — | US | disclosed |
| US-7270805-B1 | Skin lightening agents, compositions and methods | CONOPCO, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| EP-1678170-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | Yang Ji Chemical Company Ltd. (KR) | 2006-07-12 | — | — | EP | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |
| WO-2005033104-A1 | USE OF A COMPOUND OF FORMULA (I) AS AN INHIBITOR OF AROMATASE FOR THERAPEUTIC PURPOSES AND COMPOUNDS OF FORMULA (1) THEREAS | YANG JI CHEMICAL COMPANY, LTD (KR) | 2005-04-14 | — | — | WO | disclosed |
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | NOS1 418/4885ALDH1A1 207/4885MEN1 1149/4885 |
| US-20070231282-A1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | CUTA, TYR, MCOLN1 | NOS1 2290/4885ALDH1A1 99/4885MEN1 1988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.