Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758969 | 0.92 | NFE2L2 (0.44) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL1759117 | 0.90 | NFE2L2 (0.51) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL1759239 | 0.84 | NFE2L2 (0.49) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL1897819 | 0.81 | MGAM (0.40) | NFE2L2PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL1638838 | 0.81 | MAOA (0.51) | PTGER4PTGER3PTGER2PTGER1ERN1 | |
| SCHEMBL1759270 | 0.80 | KDM4E (0.48) | NFE2L2TRPA1PTGER4PTGER3PTGER2 | |
| SCHEMBL1637791 | 0.78 | PTPN5 (0.42) | PTGER4PTGER3PTGER2PTGER1KDM4E | |
| SCHEMBL1759281 | 0.77 | TLR4 (0.42) | NFE2L2CYP1A1CYP1A2CYP19A1KDM4E | |
| SCHEMBL1639242 | 0.75 | PTGER1 (0.44) | PTGER4PTGER3PTGER2PTGER1ERN1 | |
| SCHEMBL1759295 | 0.75 | FEN1 (0.42) | PTGER4PTGER3PTGER2PTGER1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493932-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056423-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |