Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752042 | 0.87 | CYP3A4 (0.40) | PRCPL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL3389376 | 0.82 | PRCP (0.45) | PRCPCYP3A4CYP2C9KCNH2NR1I2 | |
| SCHEMBL1816483 | 0.81 | L3MBTL1 (0.39) | L3MBTL1MEN1ALDH1A1KMT2AHCRTR1 | |
| SCHEMBL571726 | 0.81 | CYP3A4 (0.50) | PRCPCYP3A4CYP2C9KCNH2NR1I2 | |
| SCHEMBL483056 | 0.81 | ALDH1A1 (0.47) | PRCPL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL483330 | 0.81 | ALDH1A1 (0.47) | PRCPL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL1758861 | 0.78 | L3MBTL1 (0.35) | PRCPL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL15773400 | 0.77 | ALDH1A1 (0.43) | L3MBTL1MEN1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL13505338 | 0.77 | PRCP (0.41) | PRCPCYP3A4CYP2C9KCNH2NR1I2 | |
| SCHEMBL1293552 | 0.77 | PRCP (0.41) | PRCPCYP3A4CYP2C9KCNH2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499115-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | disclosed |
| EP-2499127-A1 | HEPATITIS C VIRUS INHIBITORS | Bristol-Myers Squibb Company (US) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011059850-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011059887-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |