Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060725 | 0.82 | CNR2 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5871596 | 0.82 | FFAR1 (0.49) | TAAR1FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL16315019 | 0.81 | CYP1A2 (0.45) | TAAR1FFAR1ALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL11836621 | 0.80 | MMP12 (0.58) | FFAR1CPA1LMNA | |
| SCHEMBL21447942 | 0.79 | FFAR1 (0.46) | TAAR1FFAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL24440170 | 0.78 | TSHR (0.49) | FFAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16148363 | 0.78 | GRIK1 (0.53) | TAAR1FFAR1 | |
| SCHEMBL16148362 | 0.78 | GRIK1 (0.53) | TAAR1FFAR1 | |
| SCHEMBL26896552 | 0.78 | TSHR (0.49) | FFAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7453651 | 0.78 | GRIK1 (0.53) | TAAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604595-B1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | SHIONOGI & CO (JP) | 2016-03-16 | — | — | EP | disclosed |