SCHEMBL1759130

SCHEMBL1759130

COc1ccccc1CC(O)c1cccc(-c2ccccc2)c1OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
BCHE P06276 13/20 0.46
PTGER1 P34995 2/20 0.45
PTGER4 P35408 2/20 0.45
PTGER3 P43115 2/20 0.45
PTGER2 P43116 2/20 0.45
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759387 0.85 FFAR1 (0.47) L3MBTL1KDM4EBCHEPTGER1PTGER4
SCHEMBL1638059 0.84 MGAM (0.47) L3MBTL1KDM4EBCHEPTGER1PTGER4
SCHEMBL1758874 0.84 BCHE (0.45) L3MBTL1KDM4EBCHEPTGER1MGAM
SCHEMBL27904061 0.83 ABCB1 (0.50) L3MBTL1KDM4EBCHEGAAKMT2A
SCHEMBL1759131 0.82 MGAM (0.47) L3MBTL1KDM4EBCHEPTGER1MGAM
SCHEMBL1759316 0.81 PTGER1 (0.49) L3MBTL1KDM4EBCHEPTGER1PTGER4
SCHEMBL27794252 0.80 MGAM (0.41) L3MBTL1PTGER1PTGER4PTGER3PTGER2
SCHEMBL1643988 0.79 MGAM (0.46) L3MBTL1KDM4EBCHEPTGER1PTGER4
SCHEMBL12725985 0.79 BCHE (0.57) L3MBTL1KDM4EBCHEMGAMGAA
SCHEMBL1637949 0.78 MAPK1 (0.46) L3MBTL1PTGER1PTGER4PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493933-A2 CATALYST COMPOUNDS AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2012-09-05 EP disclosed
WO-2011056424-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 WO disclosed