SCHEMBL1758874

SCHEMBL1758874

COc1ccccc1-c1cccc(C(O)Cc2ccccc2)c1OCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 10/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
KDM4E B2RXH2 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
PTGER1 P34995 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SGMS2 Q8NHU3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758872 0.85 BCHE (0.46) BCHEKDM4EL3MBTL1MAPTHTR1A
SCHEMBL1759130 0.84 L3MBTL1 (0.47) BCHEKDM4EL3MBTL1MGAMGAA
SCHEMBL1758876 0.82 BCHE (0.46) BCHEKDM4EL3MBTL1MAPTHTR1A
SCHEMBL1759387 0.81 FFAR1 (0.47) BCHEKDM4EL3MBTL1FFAR1MGAM
SCHEMBL1638059 0.80 MGAM (0.47) BCHEKDM4EL3MBTL1FFAR1HTR1A
SCHEMBL5667378 0.79 CYP2D6 (0.56) BCHECYP2D6CYP2C19L3MBTL1GAA
SCHEMBL1759131 0.77 MGAM (0.47) BCHEKDM4EL3MBTL1FFAR1HTR1A
SCHEMBL1638070 0.77 BCHE (0.50) BCHEKDM4EL3MBTL1MAPTHTR1A
SCHEMBL1639591 0.75 HTR1A (0.58) KDM4EL3MBTL1MAPTHTR1AADRA1D
SCHEMBL27904061 0.75 ABCB1 (0.50) BCHEKDM4EL3MBTL1MAPTHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493933-A2 CATALYST COMPOUNDS AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2012-09-05 EP disclosed
WO-2011056424-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 WO disclosed