SCHEMBL1759387

SCHEMBL1759387

COc1ccccc1C(O)Cc1cccc(-c2cccc(-c3ccccc3)c2OCc2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.47
MGAM O43451 3/20 0.46
GAA P10253 3/20 0.46
SI P14410 3/20 0.46
MGAM2 Q2M2H8 3/20 0.46
PTGER1 P34995 3/20 0.46
PTGER4 P35408 2/20 0.46
PTGER3 P43115 2/20 0.46
PTGER2 P43116 2/20 0.46
KDM4E B2RXH2 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTR7 P34969 3/20 0.44
BCHE P06276 5/20 0.42
ERN1 O75460 1/20 0.42
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1759130 0.85 L3MBTL1 (0.47) MGAMGAASIMGAM2PTGER1
SCHEMBL1638059 0.83 MGAM (0.47) FFAR1MGAMGAASIMGAM2
SCHEMBL1758874 0.81 BCHE (0.45) FFAR1MGAMGAASIMGAM2
SCHEMBL1759131 0.81 MGAM (0.47) FFAR1MGAMGAASIMGAM2
SCHEMBL12725985 0.79 BCHE (0.57) MGAMGAASIMGAM2KDM4E
SCHEMBL1759316 0.79 PTGER1 (0.49) FFAR1MGAMGAASIMGAM2
SCHEMBL1643988 0.78 MGAM (0.46) FFAR1MGAMGAASIMGAM2
SCHEMBL1638577 0.77 HTR7 (0.45) FFAR1MGAMGAASIMGAM2
SCHEMBL27794252 0.76 MGAM (0.41) FFAR1MGAMGAASIMGAM2
SCHEMBL1637949 0.76 MAPK1 (0.46) FFAR1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493932-A2 CATALYST COMPOUNDS AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2012-09-05 EP disclosed
WO-2011056423-A2 CATALYST COMPOUNDS AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-05-12 WO disclosed