SCHEMBL1759144

SCHEMBL1759144

[CH2]OS(=O)(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15352317 0.81 CA1 (0.33)
SCHEMBL758884 0.72 CA2 (0.41)
SCHEMBL2085247 0.72 CA2 (0.41)
SCHEMBL758883 0.72 CA2 (0.41)
SCHEMBL160 0.72 CA2 (0.41)
SCHEMBL9146312 0.71 CA1 (0.37)
SCHEMBL15353336 0.71 CA2 (0.36)
SCHEMBL8477658 0.69 CA2 (0.44)
SCHEMBL6448264 0.69 CA2 (0.39)
SCHEMBL6830251 0.69 CA2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985888-A Camptothecin compounds with combined topoisomarase I inhibition and DNA alkylation properties RESEARCH TRIANGLE INSTITUTE (US) 1999-11-16 US claimed
CN-109476680-B Organic magnesium phosphide, process for producing the same, complex thereof, process for producing the same, and process for producing organic phosphorus compound using the same 北兴化学工业株式会社 2022-06-28 CN disclosed
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed
US-9565856-B2 Tetrazolinone compounds and its use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-14 US disclosed
US-9017645-B2 Homoglutamic acid derivatives PIRAMAL IMAGING SA (CH) 2015-04-28 US disclosed
EP-2841429-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-20150051171-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-02-19 US disclosed
WO-2013162072-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
US-20130071327-A1 HOMOGLUTAMIC ACID DERIVATIVES PIRAMAL IMAGING SA (CH) 2013-03-21 US disclosed
EP-2499113-A1 HOMOGLUTAMIC ACID DERIVATIVES Bayer Pharma Aktiengesellschaft (DE) 2012-09-19 EP disclosed
WO-2005064008-A1 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-07-14 WO disclosed
EP-1509537-A2 CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH GILEAD SCIENCES, INC. (US) 2005-03-02 EP disclosed
US-20040143116-A1 Sulfamoyl compounds and agricultural and horticultural fungicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-07-22 US disclosed
WO-2003090690-A2 CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
US-6620812-B2 Such as 1-(N,N-dimethylsulfamoyl)-3-(2-methyl-3-chloroindol-1-yl)sulfonyl-1,2,4 -triazole NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-16 US disclosed
US-20020103243-A1 Sulfamoyl compounds and agricultural and horticultural fungicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-08-01 US disclosed
US-6350748-B1 1-(SULFAMOYL)-3-(SULFONYL)-1,2,4-TRIAZOLE DERIVATIVES NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2002-02-26 US disclosed
EP-1031571-A1 SULFAMOYL COMPOUNDS AND AGRICULTURAL OR HORTICULTURAL BACTERICIDE Nissan Chemical Industries, Ltd. (JP) 2000-08-30 EP disclosed
US-4937331-A Chemical intermediates for antibiotics PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1990-06-26 US disclosed
EP-0334593-A1 Chiral azetidinone epoxides THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1989-09-27 EP disclosed