SCHEMBL2085247

SCHEMBL2085247

O=S(=O)(OOS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
CA7 P43166 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721777 0.86 CA1 (0.37) CA2CA1CA7CA13
SCHEMBL9936351 0.85 USP2 (0.33) CA2CA1CA7CA13
SCHEMBL1345425 0.83 CA1 (0.35) CA2CA1CA7CA13
SCHEMBL28239207 0.81 CA1 (0.33) CA2CA1CA7CA13
SCHEMBL4245730 0.81 F2 (0.33) CA2CA1CA7CA13
SCHEMBL5536943 0.81 CA1 (0.33) CA2CA1CA7CA13ALDH1A1
SCHEMBL758883 0.77 CA2 (0.41) CA2CA1CA7CA13ALDH1A1
SCHEMBL160 0.77 CA2 (0.41) CA2CA1CA7CA13ALDH1A1
SCHEMBL758884 0.77 CA2 (0.41) CA2CA1CA7CA13ALDH1A1
SCHEMBL3361727 0.76 CA1 (0.30) CA2CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730890-A Optically active trifluoromethanesulfonyl peroxide derivative and preparation method thereof 西湖大学 2023-09-12 CN claimed
US-4406825-A FLUORINE-CONTAINING PEROXIDE ALLIED CORPORATION (US) 1983-09-27 US claimed
US-4269738-A MODIFYING A SOLID POLYACETYLENE WITH A FLUORINE-CONTAINING PEROXIDE, E.G. BISFLUOROSULFURYL PEROXIDE, IN A SOLVENT AT LOW TEMPERATURES AND PRESSURES; METAL-LIKE; SEMICONDUCTORS ALLIED CHEMICAL CORPORATION (US) 1981-05-26 US claimed
CN-122079960-A Alkynyl quinazoline compounds 2026-05-26 CN disclosed
EP-4013749-B1 ALKYNYL QUINAZOLINE COMPOUNDS BLACK DIAMOND THERAPEUTICS INC (US) 2026-03-11 EP disclosed
EP-3868384-B1 CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS TAKEDA PHARMACEUTICALS CO (JP) 2026-02-25 EP disclosed
US-20260049063-A1 ALKYNYL QUINAZOLINE COMPOUNDS BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-19 US disclosed
US-12435063-B2 Nitrogen containing heterocycles as CDK12 inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-10-07 US disclosed
US-12435046-B2 Alkynyl quinazoline compounds BLACK DIAMOND THERAPEUTICS, INC. (US) 2025-10-07 US disclosed
US-20250205270-A1 ANTIBODY-DRUG CONJUGATE PRECURSORS COMPRISING A CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-06-26 US disclosed
CN-119390683-A Alkynyl quinazoline compounds 黑钻治疗公司 2025-02-07 CN disclosed
US-8309714-B2 Process for producing laurolactam UBE INDUSTRIES, LTD. (JP) 2012-11-13 US disclosed
US-8163899-B2 Process for producing laurolactam NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2012-04-24 US disclosed
EP-2346869-A2 5-OXAZOLIDIN-2-ONE SUBSTITUTED 1,3,8-TRIAZASPIRO [4.5] DECAN-4-ONE DERIVATIVES USEFUL AS ORL-1 RECEPTOR MODULATORS Janssen Pharmaceutica, N.V. (BE) 2011-07-27 EP disclosed
US-20100267944-A1 PROCESS FOR PRODUCING LAUROLACTAM UBE INDUSTRIES, LTD. (JP) 2010-10-21 US disclosed
US-20100076003-A1 5-OXAZOLIDIN-2-ONE SUBSTITUTED 1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE DERIVATIVES USEFUL AS ORL-1 RECEPTOR MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2010-03-25 US disclosed
WO-2010033451-A2 5-OXAZOLIDIN-2-ONE SUBSTITUTED 1,3,8-TRIAZASPIRO [4.5] DECAN-4-ONE DERIVATIVES USEFUL AS ORL-1 RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2010-03-25 WO disclosed
US-20080103123-A1 New compounds BIOVITRUM (SE) 2008-05-01 US disclosed
US-4406825-A FLUORINE-CONTAINING PEROXIDE ALLIED CORPORATION (US) 1983-09-27 US disclosed
US-4269738-A MODIFYING A SOLID POLYACETYLENE WITH A FLUORINE-CONTAINING PEROXIDE, E.G. BISFLUOROSULFURYL PEROXIDE, IN A SOLVENT AT LOW TEMPERATURES AND PRESSURES; METAL-LIKE; SEMICONDUCTORS ALLIED CHEMICAL CORPORATION (US) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435046-B2 Alkynyl quinazoline compounds GLS, GLS2, MCL1 CA2 2340/4885CA1 3977/4885CA7 3171/4885
US-20250205270-A1 ANTIBODY-DRUG CONJUGATE PRECURSORS COMPRISING A CYCLIC DINUCLEOTIDE STING1, CGAS, TLR9 CA2 3143/4885CA1 4398/4885CA7 2841/4885
US-20100076003-A1 5-OXAZOLIDIN-2-ONE SUBSTITUTED 1,3,8-TRIAZASPIRO[4.5]DECAN-4-ONE DERIVATIVES USEFUL AS ORL-1 RECEPTOR MODULATORS OXER1, OGFRL1, ORMDL3 CA2 3409/4885CA1 4380/4885CA7 4777/4885
US-20080103123-A1 New compounds GPR119, GPR139, GPR180 CA2 1045/4885CA1 2523/4885CA7 2189/4885
US-12435063-B2 Nitrogen containing heterocycles as CDK12 inhibitors CDK1, CDK12, CDK15 CA2 1739/4885CA1 3300/4885CA7 3435/4885
US-20260049063-A1 ALKYNYL QUINAZOLINE COMPOUNDS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, BCL6 CA2 546/4885CA1 2432/4885CA7 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.