Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380088 | 0.89 | MAOA (0.42) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL17468379 | 0.82 | ELANE (0.41) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL17593127 | 0.80 | ELANE (0.50) | ELANENPSR1LMNAMAOAMAOB | |
| SCHEMBL16175012 | 0.79 | ELANE (0.51) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL16174837 | 0.79 | ELANE (0.51) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL287441 | 0.78 | LMNA (0.39) | ELANELMNA | |
| SCHEMBL16174946 | 0.77 | ELANE (0.50) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL16174789 | 0.77 | ELANE (0.46) | ELANENPSR1MMP2MMP9MMP8 | |
| SCHEMBL17550614 | 0.76 | ELANE (0.40) | ELANELMNAHSD11B1HTR7 | |
| SCHEMBL16174809 | 0.73 | ELANE (0.49) | ELANENPSR1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| CN-107075037-B | Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof | 赛鲁斯股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | claimed |
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2019-06-04 | — | — | US | claimed |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-09-28 | — | — | US | claimed |
| EP-3191533-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | claimed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| US-11021617-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | SIRRUS, INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3774715-A1 | HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | Sirrus, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |
| CN-107075037-B | Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof | 赛鲁斯股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | disclosed |
| WO-2019195366-A1 | HETEROGENEOUS CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. (US) | 2019-10-10 | — | — | WO | disclosed |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| EP-3191533-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2017-07-19 | — | — | EP | disclosed |
| US-9416091-B1 | Catalytic transesterification of ester compounds with groups reactive under transesterification conditions | SIRRUS, INC. (US) | 2016-08-16 | — | — | US | disclosed |
| WO-2016126624-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. (US) | 2016-08-11 | — | — | WO | disclosed |
| US-20160229786-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160221922-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | SIRRUS, INC. | 2016-08-04 | — | — | US | disclosed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308802-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | PCBP1, PARG, PARP1 | ELANE 2503/4885NPSR1 2445/4885MMP2 4856/4885 |
| US-20160229786-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NOTUM, CES1, CYP4F11 | ELANE 329/4885NPSR1 3753/4885MMP2 1822/4885 |
| US-20170275446-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | PCBP1, PARG, PARP1 | ELANE 2503/4885NPSR1 2445/4885MMP2 4856/4885 |
| US-20160221922-A1 | CATALYTIC TRANSESTERIFICATION OF ESTER COMPOUNDS WITH GROUPS REACTIVE UNDER TRANSESTERIFICATION CONDITIONS | NOTUM, CES1, CYP4F11 | ELANE 329/4885NPSR1 3753/4885MMP2 1822/4885 |
| US-11021617-B2 | Polymers including one or more 1,1-disubstituted alkene compounds and polymer compositions thereof | PCBP1, PARG, PARP1 | ELANE 2481/4885NPSR1 2559/4885MMP2 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.