Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530770 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL530772 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL17593083 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL4026225 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL4026231 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL530769 | 0.94 | RAB9A (0.53) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL17593078 | 0.94 | RAB9A (0.53) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| Octanoic Acid SCHEMBL30504818 | 0.94 | GAA (0.55) | ALDH1A1KMT2AMEN1RECQLHPGD | |
| SCHEMBL4026223 | 0.93 | RAB9A (0.54) | ALDH1A1KMT2AMEN1RECQLNPC1 | |
| SCHEMBL994155 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1RECQLNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040814-A2 | DISULFIDE POLYMERS AND METHODS OF USE | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2016-03-17 | — | — | WO | disclosed |