Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132591 | 0.82 | CA1 (0.31) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL778573 | 0.81 | ALDH1A1 (0.46) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL575704 | 0.81 | CA1 (0.33) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL14779233 | 0.81 | CA1 (0.43) | CA1CA2CA9ALDH1A1CXCR2 | |
| Hydrogen Sulfide SCHEMBL16193905 | 0.80 | CA1 (0.30) | CA1CA2CA9 | |
| SCHEMBL778307 | 0.79 | CA1 (0.32) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL15282823 | 0.77 | CA1 (0.36) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL21801671 | 0.77 | ALDH1A1 (0.36) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL21801399 | 0.77 | ALDH1A1 (0.36) | CA1CA2CA9ALDH1A1CXCR2 | |
| SCHEMBL14780351 | 0.77 | CA1 (0.35) | CA1CA2CA9ALDH1A1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499113-A1 | HOMOGLUTAMIC ACID DERIVATIVES | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011057986-A1 | HOMOGLUTAMIC ACID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-19 | — | — | WO | disclosed |