Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113529 | 0.84 | ALDH1A1 (0.75) | MAPTPOLBKMT2AKDM4EMEN1 | |
| SCHEMBL396527 | 0.82 | CFTR (0.60) | POLBKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6225199 | 0.77 | POLB (0.72) | MAPTPOLBTP53KMT2AKDM4E | |
| SCHEMBL29753973 | 0.77 | CFTR (0.63) | KMT2AMEN1HTR2CHRH3 | |
| SCHEMBL4430677 | 0.76 | CFTR (0.80) | KMT2AMEN1ALDH1A1HTR2CHRH3 | |
| SCHEMBL17593240 | 0.76 | NPC1 (0.60) | MAPTPOLBTP53KMT2AKDM4E | |
| SCHEMBL17593284 | 0.74 | KMT2A (0.62) | MAPTPOLBTP53KMT2AKDM4E | |
| SCHEMBL20567516 | 0.74 | STING1 (0.64) | KMT2AMEN1HTR2CHRH3 | |
| SCHEMBL20567521 | 0.74 | STING1 (0.64) | MAPTPOLBKMT2AKDM4EMEN1 | |
| SCHEMBL20567704 | 0.74 | STING1 (0.64) | KMT2AMEN1HTR2CHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040449-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |