Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.68 |
| ▸ | DPP4 | P27487 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223534 | 0.81 | CA1 (0.71) | KMT2AKDM4EMEN1ALDH1A1CA1 | |
| SCHEMBL6225889 | 0.79 | ALDH1A1 (0.78) | POLBKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8665327 | 0.78 | CA1 (0.74) | RXFP1KMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL6223450 | 0.78 | CA1 (1.00) | POLBKMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL6224243 | 0.78 | CA1 (0.66) | POLBKMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL6227739 | 0.78 | CA1 (0.66) | RXFP1KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL17593142 | 0.77 | MAPT (0.66) | POLBTP53RXFP1DPP4KMT2A | |
| SCHEMBL6226099 | 0.77 | LMNA (0.69) | TP53KMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL4123540 | 0.76 | L3MBTL1 (1.00) | POLBTP53KMT2AKDM4EMEN1 | |
| SCHEMBL29552057 | 0.75 | TP53 (0.76) | POLBTP53KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775110-B1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | EP | claimed |
| EP-0775110-B1 | ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS | WARNER LAMBERT CO (US) | 2005-10-05 | — | — | EP | disclosed |
| US-5929114-A | ADMINISTERING ANTIVIRAL COMPOUND WHICH EXTRUDES ZINC FROM NUCLEOCAPSID PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS | WARNER-LAMBERT COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5734081-A | Arylthio compounds | WARNER-LAMBERT COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5668291-A | THIOSUBSTITUTED PYRIDINES, TREATMENT OF AIDS AND HIV | WARNER-LAMBERT COMPANY (US) | 1997-09-16 | — | — | US | disclosed |