Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21239553 | 0.79 | KCNN2 (0.38) | — | |
| SCHEMBL18489595 | 0.77 | BACE1 (0.41) | — | |
| SCHEMBL1069878 | 0.77 | BACE1 (0.41) | — | |
| SCHEMBL19920167 | 0.76 | HTR7 (0.64) | HTR7CASRDRD2DRD4DRD3 | |
| SCHEMBL1758905 | 0.73 | TAAR1 (0.37) | — | |
| SCHEMBL1759325 | 0.73 | HTR7 (0.55) | HTR7CASRDRD2DRD4DRD3 | |
| SCHEMBL1638847 | 0.71 | KAT6A (0.42) | HTR7CASRPTPN5PTPRCPTPN1 | |
| SCHEMBL1638845 | 0.71 | KAT6A (0.42) | HTR7CASRPTPN5PTPRCPTPN1 | |
| SCHEMBL12726511 | 0.71 | KAT6A (0.42) | HTR7CASRPTPN5PTPRCPTPN1 | |
| SCHEMBL12806502 | 0.71 | HTR7 (0.69) | HTR7CASRDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493932-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056423-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |