Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.55 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR1E | P28566 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR5A | P47898 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3338228 | 0.79 | HTR7 (0.74) | HTR7CASRFFAR1HTR1AHTR1D | |
| SCHEMBL12881923 | 0.75 | HTR7 (0.71) | HTR7CASRFFAR1HTR1AHTR1D | |
| SCHEMBL22398944 | 0.75 | HTR7 (0.71) | HTR7CASRFFAR1HTR1ADRD2 | |
| SCHEMBL1759143 | 0.75 | HRH3 (0.43) | HTR7FFAR1KDM4EMAPT | |
| SCHEMBL1638864 | 0.74 | CASR (0.52) | HTR7CASRLPAR1PTPN5PTPRC | |
| SCHEMBL9230739 | 0.74 | HTR7 (0.69) | HTR7CASRFFAR1HTR1ADRD2 | |
| SCHEMBL1759322 | 0.73 | HTR7 (0.50) | HTR7CASRFFAR1DRD2DRD4 | |
| SCHEMBL12806502 | 0.72 | HTR7 (0.69) | HTR7CASRFFAR1HTR1ADRD2 | |
| SCHEMBL10287112 | 0.71 | HTR7 (0.66) | HTR7CASRFFAR1HTR1ADRD2 | |
| SCHEMBL3338568 | 0.71 | HTR7 (1.00) | HTR7CASRFFAR1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493932-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056423-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |