⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694335 | 0.74 | — | — | |
| SCHEMBL11603028 | 0.74 | — | — | |
| SCHEMBL23875459 | 0.72 | — | — | |
| SCHEMBL10342373 | 0.71 | — | — | |
| SCHEMBL1023944 | 0.69 | CYP2C19 (0.32) | — | |
| SCHEMBL23082007 | 0.67 | — | — | |
| SCHEMBL8719874 | 0.65 | — | — | |
| SCHEMBL21570581 | 0.65 | — | — | |
| SCHEMBL9336628 | 0.64 | — | — | |
| SCHEMBL3252658 | 0.64 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875510-B | Method for preparing aminoacetaldehyde dimethyl acetal | 厦门优孚利生物医药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-112010741-A | Method for improving purity of chloroacetaldehyde dimethyl acetal by vinyl acetate method | 石家庄欧特佳化工有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-117088815-A | Preparation method of methimazole | 南京仁为医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-116368162-A | Resin composition for secondary battery electrode | 积水化学工业株式会社 | 2023-06-30 | — | — | CN | disclosed |
| CN-111875510-B | Method for preparing aminoacetaldehyde dimethyl acetal | 厦门优孚利生物医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-113968870-A | Clean method capable of synthesizing 3, 4-vinyl dioxythiophene on large scale | 上海漫关越水处理有限公司 | 2022-01-25 | — | — | CN | disclosed |
| US-10882809-B2 | Production method for halogenated alpha-fluoroethers | CENTRAL GLASS COMPANY, LIMITED (JP) | 2021-01-05 | — | — | US | disclosed |
| CN-112010740-A | Green process technology for preparing chloroacetaldehyde dimethyl acetal from vinyl chloride | 石家庄欧特佳化工有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-112010741-A | Method for improving purity of chloroacetaldehyde dimethyl acetal by vinyl acetate method | 石家庄欧特佳化工有限公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-111875510-A | Method for preparing aminoacetaldehyde dimethyl acetal | 厦门优孚利生物医药科技有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-107602476-B | Preparation method of 2-mercapto-1-methylimidazole | 浦拉司科技（上海）有限责任公司 | 2020-06-26 | — | — | CN | disclosed |
| US-20120252739-A1 | Tubulin Inhibitors | R&D BIOPHARMACEUTICALS GMBH (DE) | 2012-10-04 | — | — | US | disclosed |
| EP-2499153-A1 | TUBULIN INHIBITORS | R & D Biopharmaceuticals Gmbh (DE) | 2012-09-19 | — | — | EP | disclosed |
| EP-2499152-A1 | TUBULIN INHIBITORS | R & D Biopharmaceuticals Gmbh (DE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011057806-A1 | TUBULIN INHIBITORS | R&D BIOPHARMACEUTICALS GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011057805-A1 | TUBULIN INHIBITORS | R&D BIOPHARMACEUTICALS GMBH (DE) | 2011-05-19 | — | — | WO | disclosed |
| EP-2322537-A1 | Tubulin inhibitors | R & D Biopharmaceuticals Gmbh (DE) | 2011-05-18 | — | — | EP | disclosed |
| US-5116402-A | HERBICIDAL COMPOSITION CONTAINING DIOXOLANE, DIOXANE, OR DIOXEPANE DERIVATIVES AS ANTIDOTE | MAGYAR TUDOMANVOS AKADEMIA KOZPONTI KEMIAI KUTATO INTEZETE NITROKEMIA INARTELENEK FUZFOGYARTELEP (HU) | 1992-05-26 | — | — | US | disclosed |
| EP-0054278-B1 | PLANT PROTECTING AGENTS FOR USE DURING WEED CONTROL, 2-(DICHLOROMETHYL)-3-PHENYL-1,3-OXAZOLIDINE AND 2-(DICHLOROMETHYL)-3-ALLYL-1,3-OXAZOLIDINE, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS COMPRISED IN SAID AGENTS AS ANTIDOTES, OR OF THE LATTER MENTIONED COMPOUNDS | MAGYAR TUDOMANYOS AKADEMIA KÖZP KEMIAI KUTATO INTEZET (HU) | 1987-04-01 | — | — | EP | disclosed |
| EP-0054278-A1 | Plant protecting agents for use during weed control, 2-(dichloromethyl)-3-phenyl-1,3-oxazolidine and 2-(dichloromethyl)-3-allyl-1,3-oxazolidine, and method for the preparation of the compounds comprised in said agents as antidotes, or of the latter mentioned compounds | MAGYAR TUDOMANYOS AKADEMIA KÖZP KEMIAI KUTATO INTEZET (HU) | 1982-06-23 | — | — | EP | disclosed |