SCHEMBL1023944

SCHEMBL1023944

COC(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31555956 0.72
SCHEMBL1759333 0.69
SCHEMBL31555958 0.67
SCHEMBL23082007 0.67
SCHEMBL6694335 0.67
SCHEMBL24113436 0.65
SCHEMBL8719874 0.65
SCHEMBL21570581 0.65
SCHEMBL11911972 0.64 ALDH1A1 (0.33)
SCHEMBL13731004 0.61 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4874902-A FLUORINATION WITH CHLORINE OR BROMINE TRIFLUORIDE BOC, INC. (US) 1989-10-17 US claimed
EP-2036877-B1 Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether HALOCARBON PROD CORP (US) 2015-08-12 EP disclosed
EP-2272816-A1 Removal of water from a mixture comprising hydrogen fluoride and water Halocarbon Products Corporation (US) 2011-01-12 EP disclosed
EP-2036877-A2 Production of fluormethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether Halocarbon Products Corporation (US) 2009-03-18 EP disclosed
EP-1268381-B1 PRODUCTION OF FLUORMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL ETHER HALOCARBON PROD CORP (US) 2008-12-31 EP disclosed
EP-1268381-A4 PRODUCTION OF FLUORMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL ETHER HALOCARBON PROD CORP (US) 2004-10-20 EP disclosed
EP-1268381-A1 PRODUCTION OF FLUORMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL ETHER Halocarbon Products Corporation (US) 2003-01-02 EP disclosed
US-6469219-B1 REACTING A MIXTURE COMPRISING 1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL, FORMALDEHYDE AND HYDROGEN FLUORIDE IN THE ABSENCE OF A DEHYDRATING, PROTONATING OR FLUORIDE ION GENERATING AGENT; SOLVENT EXTRACTION HALOCARBON PRODUCTS CORPORATION 2002-10-22 US disclosed
WO-2001068577-A1 PRODUCTION OF FLUORMETHYL 2,2,2-TRIFLUORO-1-(TRIFLUOROMETHYL)ETHYL ETHER HALOCARBON PRODUCTS CORPORATION (US) 2001-09-20 WO disclosed
US-4874902-A FLUORINATION WITH CHLORINE OR BROMINE TRIFLUORIDE BOC, INC. (US) 1989-10-17 US disclosed
US-4874902-A FLUORINATION WITH CHLORINE OR BROMINE TRIFLUORIDE BOC, INC. (US) 1989-10-17 US disclosed