Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458236 | 0.88 | MAOB (0.52) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL20598466 | 0.87 | MAOB (0.54) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL1556056 | 0.87 | MAOB (0.54) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL27809104 | 0.87 | MAPK1 (0.52) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL27876784 | 0.86 | KMT2A (0.48) | MAOBMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28416934 | 0.86 | ALDH1A1 (0.57) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL28409395 | 0.84 | MAOB (0.51) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5583398 | 0.84 | ALDH1A1 (0.57) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL6327015 | 0.84 | MAOB (0.51) | MAOBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8643962 | 0.84 | MAOB (0.51) | MAOBMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903608-A1 | ESTERS OF SHORT CHAINS FATTY ACIDS FOR USE IN THE TREATMENT OF IMMUNOGENIC DISORDERS | Proponent Biotech GmbH (CH) | 2015-08-12 | — | — | EP | claimed |
| WO-2014053592-A1 | ESTERS OF SHORT CHAINS FATTY ACIDS FOR USE IN THE TREATMENT OF IMMUNOGENIC DISORDERS | PROPONENT BIOTECH GMBH (CH) | 2014-04-10 | — | — | WO | claimed |
| CN-107698766-B | Branched polyorganosiloxanes and related curable compositions, methods, uses and devices | 美国陶氏有机硅公司 | 2021-02-23 | — | — | CN | disclosed |
| EP-3004275-B1 | IN SITU METHOD FOR FORMING THERMALLY CONDUCTIVE THERMAL RADICAL CURE SILICONE COMPOSITION | DOW SILICONES CORP (US) | 2020-10-21 | — | — | EP | disclosed |
| CN-106957594-B | Surface treatment composition, method of preparing surface treatment composition, and surface-treated article | 美国陶氏有机硅公司 | 2020-03-03 | — | — | CN | disclosed |
| EP-2954023-B1 | STABLE THERMAL RADICAL CURABLE SILICONE ADHESIVE COMPOSITIONS | DOW SILICONES CORP (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-2499209-B1 | SURFACE TREATMENT COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND SURFACE-TREATED ARTICLE | ESSILOR INT (FR) | 2019-08-21 | — | — | EP | disclosed |
| WO-2019151442-A1 | FLUORO (POLY)ETHER GROUP-CONTAINING SILANE COMPOUND | ダイキン工業株式会社 | 2019-08-08 | — | — | WO | disclosed |
| WO-2019151445-A1 | ELECTRONIC DEVICE | ダイキン工業株式会社 | 2019-08-08 | — | — | WO | disclosed |
| US-10370574-B2 | Method for forming thermally conductive thermal radical cure silicone compositions | DOW SILICONES CORPORATION (US) | 2019-08-06 | — | — | US | disclosed |
| EP-2954024-B1 | CURABLE SILICONE COMPOSITIONS COMPRISING CLUSTERED FUNCTIONAL POLYORGANOSILOXANES AND SILICONE REACTIVE DILUENTS | DOW SILICONES CORP (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20130004780-A1 | Surface Treatment Composition, Process For Producing The Same, And Surface-Treated Article | ESSILOR INTERNATIONAL (FR) | 2013-01-03 | — | — | US | disclosed |
| EP-2499209-A1 | SURFACE TREATMENT COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND SURFACE-TREATED ARTICLE | Essilor International (Compagnie Générale D'Optique) (FR) | 2012-09-19 | — | — | EP | disclosed |
| CN-102666759-A | Surface treatment composition, process for producing the same, and surface-treated article | ESSILOR INT | 2012-09-12 | — | — | CN | disclosed |
| WO-2012064989-A1 | SURFACE TREATMENT COMPOSITION, METHOD OF PRODUCING THE SURFACE TREATMENT COMPOSITION, AND SURFACE-TREATED ARTICLE | DOW CORNING CORPORATION (US) | 2012-05-18 | — | — | WO | disclosed |
| WO-2011060047-A1 | SURFACE TREATMENT COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND SURFACE-TREATED ARTICLE | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 2011-05-19 | — | — | WO | disclosed |
| US-7514566-B2 | Thiazole compounds and methods of use | AMGEN, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070173506-A1 | Thiazole compounds and methods of use | AMGEN INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-6191220-B1 | REACTING POLYMER HAVING OLEFINIC OR ACETYLENIC UNSATURATED GROUPS WITH HYDRIDE (HYDROCARBONOXY) SILANE IN PRESENCE OF PLATINUM OR PLATINUM COMPOUND CATALYST AND SILYLATED CARBOXYLIC ACID TO FORM HYDROCARBONOXYSILYL FUNCTIONAL POLYMER | DOW CORNING ASIA, LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| US-5994573-A | Method for making triarylamine compounds having hydrocarbonoxysilyl groups | DOW CORNING ASIA, LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173506-A1 | Thiazole compounds and methods of use | MTOR, JAK2, PCK2 | MAOB 2482/4885MEN1 1825/4885KMT2A 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.