Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14740870 | 0.88 | PARP1 (0.39) | PARP1KDM4EALDH1A1POLBTDP1 | |
| SCHEMBL17594868 | 0.85 | KIF11 (0.38) | PARP1ALDH1A1L3MBTL1PARP2LMNA | |
| SCHEMBL17594969 | 0.84 | KIF11 (0.39) | PARP1ALDH1A1PARP2LMNAMEN1 | |
| SCHEMBL17595085 | 0.84 | PARP1 (0.32) | PARP1PARP2 | |
| SCHEMBL14740829 | 0.81 | SLC16A3 (0.45) | PARP1KDM4EALDH1A1POLBTDP1 | |
| SCHEMBL14745174 | 0.79 | KCNH2 (0.40) | PARP1ALDH1A1POLBMAPTPARP2 | |
| SCHEMBL14741099 | 0.79 | PARP1 (0.41) | PARP1KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL14745530 | 0.78 | KDM4E (0.39) | PARP1KDM4EALDH1A1PARP2TNKS | |
| SCHEMBL14747044 | 0.77 | KIF11 (0.41) | PARP1ALDH1A1POLBL3MBTL1MAPT | |
| SCHEMBL14745092 | 0.77 | PARP1 (0.43) | PARP1ALDH1A1L3MBTL1MAPTPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016039936-A2 | MONOCYCLIC SUBSTITUTED 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | claimed |