Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14745525 | 0.96 | PDE3B (0.34) | PDE3BPDE3ACHRM4 | |
| SCHEMBL16568463 | 0.94 | PDE3B (0.34) | PDE3BPDE3ACHRM4 | |
| Trifluoroacetic Acid SCHEMBL14741213 | 0.90 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL16568180 | 0.89 | PDE3B (0.35) | PDE3BPDE3A | |
| Trifluoroacetic Acid SCHEMBL14745524 | 0.85 | PDE3B (0.33) | PDE3BPDE3A | |
| SCHEMBL17594910 | 0.84 | CACNA1B (0.33) | PDE3BPDE3A | |
| SCHEMBL17595147 | 0.84 | CACNA1B (0.33) | PDE3BPDE3A | |
| SCHEMBL16568064 | 0.84 | PDE3B (0.35) | PDE3BPDE3A | |
| Trifluoroacetic Acid SCHEMBL14741089 | 0.83 | MCHR1 (0.34) | PDE3BPDE3A | |
| SCHEMBL17594875 | 0.83 | CACNA1B (0.38) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016039936-A2 | MONOCYCLIC SUBSTITUTED 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | claimed |