Piperidine

Piperidine

SCHEMBL17595656

C1CCNCC1.O=Cc1cccc2ccccc12

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
TTR P02766 1/20 0.42
AKR1B1 P15121 1/20 0.42
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
CYP1A2 P05177 1/20 0.41
HTR1A P08908 1/20 0.41
CYP2D6 P10635 1/20 0.41
NCF1 P14598 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
HTR2A P28223 1/20 0.41
HTR7 P34969 1/20 0.41
MTOR P42345 1/20 0.41
HTR3A P46098 1/20 0.41
HTR5A P47898 1/20 0.41
HTR6 P50406 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ortho-Phthalaldehyde SCHEMBL7621085 0.83 LMNA (0.59) MEN1KMT2ATSHRHTR2ALMNA
SCHEMBL35849993 0.83 MEN1 (0.57) MEN1KMT2ATTRAKR1B1TSHR
SCHEMBL9005 0.83 MEN1 (0.57) MEN1KMT2ATTRAKR1B1TSHR
Hydrochloric Acid SCHEMBL10384676 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
SCHEMBL3107253 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
SCHEMBL3109583 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
SCHEMBL11132298 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
SCHEMBL3115624 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
Potassium SCHEMBL31317026 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR
Phosphine SCHEMBL31216406 0.81 MEN1 (0.55) MEN1KMT2ATTRAKR1B1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170248616-A1 IN VITRO COMPOSITIONS COMPRISING HUMAN SAMPLE AND AMYLOID TARGETING AGENT Amydis, Inc. 2017-08-31 US disclosed
EP-3191107-A2 IN VITRO COMPOSITIONS COMPRISING HUMAN SAMPLE AND AMYLOID TARGETING AGENT Amydis Diagnostics, Inc. (US) 2017-07-19 EP disclosed
WO-2016040891-A2 IN VITRO COMPOSITIONS COMPRISING HUMAN SAMPLE AND AMYLOID TARGETING AGENT AMYDIS DIAGNOSTICS (US) 2016-03-17 WO disclosed