Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL6694640 | 0.86 | TRIM24 (0.67) | LMNAKMT2AMEN1THRBBLM | |
| Piperidine SCHEMBL27475822 | 0.86 | LMNA (0.43) | LMNAKMT2AMEN1THRBBLM | |
| Piperidine SCHEMBL17595656 | 0.83 | MEN1 (0.42) | LMNAKMT2AMEN1THRBBLM | |
| Piperidine SCHEMBL7621076 | 0.83 | MEN1 (0.40) | LMNAKMT2AMEN1THRBBLM | |
| Piperidine SCHEMBL7619489 | 0.82 | ALDH1A1 (0.43) | LMNAKMT2AMEN1THRBBLM | |
| Pyrrolidine SCHEMBL10325882 | 0.81 | MEN1 (0.41) | LMNAKMT2AMEN1THRBBLM | |
| 2-Nitrobenzaldehyde SCHEMBL1685299 | 0.80 | ERN1 (0.50) | KMT2AMEN1TDP1ALDH1A1SMN1; SMN2 | |
| Benzaldehyde SCHEMBL28288709 | 0.80 | ALDH1A1 (0.61) | LMNAKMT2AALDH1A1TRIM24TRIM33 | |
| Pyrrolidine SCHEMBL15054617 | 0.79 | ALDH1A1 (0.44) | LMNAKMT2AMEN1THRBBLM | |
| Piperidine SCHEMBL7617787 | 0.79 | MEN1 (0.36) | LMNAKMT2AMEN1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635004-B1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMA INC (US) | 2002-07-17 | — | — | EP | claimed |
| US-5675009-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-10-07 | — | — | US | claimed |
| US-5644061-A | Process for piperidine derivatives | MERRELL PHARMACEUTICALS INC. (US) | 1997-07-01 | — | — | US | claimed |
| EP-0635004-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-25 | — | — | EP | claimed |
| WO-1993021156-A1 | 4-DIPHENYLMETHYL PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-28 | — | — | WO | claimed |