Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402380 | 0.85 | KDM4E (0.47) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL1228229 | 0.80 | KDM4E (0.50) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL18369670 | 0.78 | PSMD14 (0.51) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL12072279 | 0.78 | KDM4E (0.55) | KDM4EHTTALDH1A1SLC40A1MAP2K1 | |
| SCHEMBL17596179 | 0.78 | KDM4E (0.55) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL3502575 | 0.77 | KDM4E (0.56) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL20328552 | 0.76 | ATM (0.36) | KDM4EHTTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL29046675 | 0.75 | KDM4E (0.55) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL17596177 | 0.75 | NPC1 (0.42) | KDM4EALOX15HTTALDH1A1SLC40A1 | |
| SCHEMBL21878514 | 0.75 | KDM4E (0.55) | KDM4EALOX15HTTALDH1A1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715425-B | Herbicidal quinolines | 先正达参股股份有限公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3191465-B1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-19 | — | — | EP | disclosed |
| US-9980486-B2 | Herbicidal quinolines | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-29 | — | — | US | disclosed |
| US-20170251670-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-07 | — | — | US | disclosed |
| EP-3191465-A1 | HERBICIDAL QUINOLINES | Syngenta Participations AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| CN-106715425-A | Herbicidal quinolines | 先正达参股股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| WO-2016038173-A1 | HERBICIDAL QUINOLINES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170251670-A1 | HERBICIDAL QUINOLINES | NQO2, DDT, ATP1B1 | KDM4E 1955/4885ALOX15 2507/4885HTT 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.