Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 16/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759696 | 0.91 | GYS1 (0.55) | GYS1 | |
| SCHEMBL1759556 | 0.90 | GYS1 (0.47) | GYS1 | |
| SCHEMBL1759563 | 0.84 | GYS1 (0.49) | GYS1 | |
| SCHEMBL1760262 | 0.82 | GYS1 (0.52) | GYS1FFAR1 | |
| SCHEMBL1759586 | 0.80 | GYS1 (0.49) | GYS1 | |
| SCHEMBL1759512 | 0.75 | GYS1 (0.56) | GYS1FFAR1 | |
| SCHEMBL1760075 | 0.75 | GYS1 (0.56) | GYS1 | |
| SCHEMBL31370752 | 0.74 | KMT2A (0.55) | — | |
| SCHEMBL1760240 | 0.74 | GYS1 (0.51) | GYS1 | |
| SCHEMBL1759672 | 0.74 | GYS1 (0.53) | GYS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057959-A1 | INDOLE AND INDAZOLE DERIVATIVES AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-05-19 | — | — | WO | disclosed |