Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759556 | 0.92 | GYS1 (0.47) | GYS1 | |
| SCHEMBL1759696 | 0.89 | GYS1 (0.55) | GYS1 | |
| SCHEMBL1759705 | 0.84 | GYS1 (0.56) | GYS1 | |
| SCHEMBL1759588 | 0.83 | GYS1 (0.49) | GYS1PKM | |
| SCHEMBL1759586 | 0.78 | GYS1 (0.49) | GYS1 | |
| SCHEMBL1760262 | 0.78 | GYS1 (0.52) | GYS1 | |
| SCHEMBL1759662 | 0.76 | GYS1 (0.48) | GYS1 | |
| SCHEMBL1759511 | 0.76 | GYS1 (0.49) | GYS1 | |
| SCHEMBL7123353 | 0.74 | PKM (0.62) | PKM | |
| SCHEMBL10289733 | 0.73 | PKM (0.67) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057959-A1 | INDOLE AND INDAZOLE DERIVATIVES AS GLYCOGEN SYNTHASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-05-19 | — | — | WO | disclosed |