Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KIF20A | O95235 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597396 | 0.87 | PRKAB2 (0.40) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597319 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597424 | 0.87 | ALDH1A1 (0.42) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597772 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597733 | 0.85 | ALDH1A1 (0.43) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597961 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597788 | 0.83 | PRKAB2 (0.41) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17597114 | 0.83 | MAPT (0.40) | ALDH1A1LMNAEGFRKDRTEK | |
| SCHEMBL17598024 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKIF20ACLK1 | |
| SCHEMBL17597400 | 0.79 | FFAR4 (0.37) | ALDH1A1LMNAFFAR4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040764-A1 | CARBONYL LINKED BICYCLIC HETEROARYL N-BENZIMIDAZOLES AND ANALOGS AS ANTIBIOTIC TOLERANCE INHIBITORS | SPERO THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |