Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170269 | 0.98 | HDAC6 (0.50) | MMP14HDAC6MMP2HDAC3HDAC4 | |
| SCHEMBL1007940 | 0.98 | HDAC6 (0.50) | MMP14HDAC6MMP2HDAC3HDAC4 | |
| SCHEMBL18073570 | 0.98 | HDAC6 (0.50) | MMP14HDAC6MMP2HDAC3HDAC4 | |
| SCHEMBL2677344 | 0.94 | MMP14 (0.55) | MMP14HDAC6MMP2HDAC3HDAC4 | |
| SCHEMBL2637695 | 0.86 | TP53 (0.47) | MMP14PPARGSMN1; SMN2BCHETP53 | |
| Hydrochloric Acid SCHEMBL6831468 | 0.85 | TP53 (0.46) | MMP14PPARGKDM4AKDM4CSMN1; SMN2 | |
| SCHEMBL10905310 | 0.84 | MMP14 (0.50) | MMP14HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL31478350 | 0.84 | LMNA (0.50) | HDAC6MMP2MAPTPPARGSMN1; SMN2 | |
| SCHEMBL31478349 | 0.84 | LMNA (0.50) | HDAC6MMP2MAPTPPARGSMN1; SMN2 | |
| SCHEMBL31478356 | 0.84 | LMNA (0.50) | HDAC6MMP2MAPTPPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995612-A1 | Novel non-natural amino acids, their process of preparation and uses thereof | Université de Strasbourg (FR) | 2016-03-16 | — | — | EP | disclosed |