SCHEMBL17599174

SCHEMBL17599174

NC(=O)c1cc(N)ccc1NC(=O)c1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.54
GAA P10253 3/20 0.54
MAPK1 P28482 1/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
TDP1 Q9NUW8 3/20 0.53
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
APEX1 P27695 1/20 0.53
PDCD1 Q15116 1/20 0.53
CD274 Q9NZQ7 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
HDAC1 Q13547 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NPC1 O15118 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10598787 0.90 MAPT (0.66) MAPTMAPK1MEN1KMT2ATDP1
SCHEMBL23258276 0.83 PDCD1 (0.74) GAAMAPK1MEN1KMT2ATDP1
SCHEMBL8478104 0.82 KDM4E (0.45) MAPTGAAMEN1KMT2ATDP1
SCHEMBL301367 0.81 MAPT (0.77) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL4905569 0.79 MAPT (0.76) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL7487857 0.79 KDM4E (0.63) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL28070128 0.79 MAPT (0.69) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL28803930 0.79 MAPT (0.52) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL3880896 0.78 MAPT (0.82) MAPTGAAMAPK1MEN1KMT2A
SCHEMBL4371765 0.78 PTPN1 (0.50) MAPTGAAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10233288-B2 Highly functional polyamide polymer, spinning dope composition containing same, and molded product thereof WOOJUNG CHEM CO., LTD. (KR) 2019-03-19 US disclosed
EP-2998338-B1 HIGHLY FUNCTIONAL POLYAMIDE POLYMER, SPINNING DOPE COMPOSITION CONTAINING SAME, AND MOLDED PRODUCT THEREOF WOOJUNG CHEM CO LTD (KR) 2018-04-11 EP disclosed
US-20180009946-A1 HIGHLY FUNCTIONAL POLYAMIDE POLYMER, SPINNING DOPE COMPOSITION CONTAINING SAME, AND MOLDED PRODUCT THEREOF WOOJUNG CHEM. CO., LTD. (KR) 2018-01-11 US disclosed
US-9803054-B2 Highly functional polyamide polymer, spinning dope composition containing same, and molded product thereof WOOJUNG CHEM. CO., LTD. (KR) 2017-10-31 US disclosed
US-20160083515-A1 HIGHLY FUNCTIONAL POLYAMIDE POLYMER, SPINNING DOPE COMPOSITION CONTAINING SAME, AND MOLDED PRODUCT THEREOF WOOJUNG CHEM. CO., LTD. (KR) 2016-03-24 US disclosed
EP-2998338-A1 HIGHLY FUNCTIONAL POLYAMIDE POLYMER, SPINNING DOPE COMPOSITION CONTAINING SAME, AND MOLDED PRODUCT THEREOF Woojung Chem. Co., Ltd. (KR) 2016-03-23 EP disclosed