Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.57 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599174 | 0.90 | MAPT (0.54) | MAPTCYP1A2CYP2C9CYP2C19PDCD1 | |
| SCHEMBL7752909 | 0.88 | MAPT (0.68) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29226011 | 0.88 | MAPT (0.61) | MAPTCYP1A2CYP2C9CYP2C19PDCD1 | |
| SCHEMBL8478104 | 0.83 | KDM4E (0.45) | MAPTCYP1A2CYP2C9CYP2C19PDCD1 | |
| SCHEMBL11591501 | 0.82 | HDAC1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL786246 | 0.82 | PDCD1 (0.81) | MAPTPDCD1CD274MEN1KMT2A | |
| SCHEMBL23258276 | 0.81 | PDCD1 (0.74) | CYP1A2CYP2C19PDCD1CD274MEN1 | |
| SCHEMBL8528829 | 0.81 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29088261 | 0.81 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3529060 | 0.81 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162806-B1 | AZO COMPOUNDS CONTAINING AT LEAST ONE CARBON AMIDE GROUP | CIBA-GEIGY AG (CH) | 1989-01-25 | — | — | EP | disclosed |
| US-4737581-A | PIGMENTING HIGH-MOLECULAR-WEIGHT COMPOUNDS; PRINTING INKS; LACQUERS COLORFASTNESS; REDS AND ORANGES | CIBA-GEIGY CORPORATION (US) | 1988-04-12 | — | — | US | disclosed |
| EP-0162806-A2 | Azo compounds containing at least one carbon amide group | CIBA-GEIGY AG (CH) | 1985-11-27 | — | — | EP | disclosed |