SCHEMBL17599183

SCHEMBL17599183

O=C1NCCN1CC1CO1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
TP53 P04637 1/20 0.48
HBB P68871 1/20 0.48
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 3/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
DHFR P00374 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
ADORA2A P29274 1/20 0.36
ADORA2B P29275 1/20 0.36
ADORA1 P30542 1/20 0.36
PER2 O15055 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17599197 0.89 SMN1; SMN2 (0.45) SMN1; SMN2TP53HBBMEN1KMT2A
SCHEMBL17599198 0.82 PIM1 (0.40) SMN1; SMN2TP53HBBMEN1KMT2A
SCHEMBL28770825 0.74 TSHR (0.43) SMN1; SMN2MEN1KMT2APOLBALDH1A1
SCHEMBL3471790 0.74 TP53 (0.56) SMN1; SMN2TP53HBBALDH1A1MAPT
SCHEMBL11598636 0.74 TP53 (0.56) SMN1; SMN2TP53HBBALDH1A1MAPT
SCHEMBL11601033 0.73 TP53 (0.45) SMN1; SMN2TP53HBBMEN1KMT2A
SCHEMBL27962782 0.72 CHRNB2 (0.41) SMN1; SMN2TP53HBB
SCHEMBL28811914 0.72 CHRNB2 (0.41) SMN1; SMN2TP53HBB
SCHEMBL27962784 0.72 CHRNB2 (0.41) SMN1; SMN2TP53HBB
SCHEMBL334938 0.72 TP53 (0.48) SMN1; SMN2TP53HBBKDM4EDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2998327-B1 POLYOLEFIN MODIFIED WITH NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND ADHESIVE COMPOSITION CONTAINING SAME TOYO BOSEKI (JP) 2022-03-23 EP disclosed
US-10253114-B2 Polyolefin modified with nitrogen-containing heterocyclic compound, and adhesive composition containing same TOYOBO CO., LTD. (JP) 2019-04-09 US disclosed
US-20160130373-A1 POLYOLEFIN MODIFIED WITH NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND ADHESIVE COMPOSITION CONTAINING SAME TOYOBO CO., LTD. (JP) 2016-05-12 US disclosed
EP-2998327-A1 POLYOLEFIN MODIFIED WITH NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AND ADHESIVE COMPOSITION CONTAINING SAME TOYOBO CO., LTD. (JP) 2016-03-23 EP disclosed