Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CDA | P32320 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544564 | 0.81 | TP53 (0.48) | TP53HBBSMN1; SMN2CRBNDHFR | |
| SCHEMBL11568357 | 0.73 | CRBN (0.55) | CRBNDDB1GAACDAMEN1 | |
| SCHEMBL17599183 | 0.73 | SMN1; SMN2 (0.48) | TP53HBBSMN1; SMN2DHFRMEN1 | |
| SCHEMBL3471790 | 0.71 | TP53 (0.56) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL11598636 | 0.71 | TP53 (0.56) | TP53HBBSMN1; SMN2DHFRALDH1A1 | |
| SCHEMBL17599197 | 0.70 | SMN1; SMN2 (0.45) | TP53HBBSMN1; SMN2DHFRCDA | |
| SCHEMBL7961031 | 0.70 | CRBN (0.52) | CRBNDDB1GAAMEN1ALDH1A1 | |
| SCHEMBL22398815 | 0.69 | TP53 (0.48) | TP53HBBSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL1576503 | 0.69 | TP53 (0.48) | TP53HBBSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL4511967 | 0.68 | TP53 (0.42) | TP53HBBSMN1; SMN2CRBNGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117029-A | VINYL CHLORIDE POLYE | NITTO KASEI CO. LTD. (JP) | 1978-09-26 | — | — | US | claimed |
| US-4117029-A | VINYL CHLORIDE POLYE | NITTO KASEI CO. LTD. (JP) | 1978-09-26 | — | — | US | disclosed |