Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.32 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.32 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189265 | 0.81 | CHAT (0.34) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL2532692 | 0.79 | TTR (0.37) | CA1TTRALOX5PTGS1PTGS2 | |
| SCHEMBL27693757 | 0.78 | MAOB (0.37) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL4438933 | 0.77 | MAOB (0.39) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL7324466 | 0.76 | TRPA1 (0.37) | CA1TTRALOX5PTGS1PTGS2 | |
| SCHEMBL6837817 | 0.76 | CHAT (0.35) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL28484538 | 0.76 | CHAT (0.39) | TTRALOX5PTGS1PTGS2TRPA1 | |
| Hydrochloric Acid SCHEMBL12003783 | 0.76 | MAOB (0.38) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL30781477 | 0.76 | CHAT (0.39) | TTRALOX5PTGS1PTGS2TRPA1 | |
| SCHEMBL31506486 | 0.76 | CHAT (0.35) | TTRALOX5PTGS1PTGS2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419987-A1 | AFFINITY LIGAND FOR THE PURIFICATION OF GLYCOSYLATED BIOMOLECULES | Hochschule für Technik und Wirtschaft (HTW) Berlin (DE) | 2019-01-02 | — | — | EP | claimed |
| WO-2017144099-A1 | AFFINITY LIGAND FOR THE PURIFICATION OF GLYCOSYLATED BIOMOLECULES | HOCHSCHULE FÜR TECHNIK UND WIRTSCHAFT (HTW) BERLIN (DE) | 2017-08-31 | — | — | WO | claimed |
| EP-3419987-A1 | AFFINITY LIGAND FOR THE PURIFICATION OF GLYCOSYLATED BIOMOLECULES | Hochschule für Technik und Wirtschaft (HTW) Berlin (DE) | 2019-01-02 | — | — | EP | disclosed |
| EP-2998008-B1 | Product protective capture and elution of N-glycosylated therapeutic glycoproteins and enveloped viruses | HOCHSCHULE FÜR TECHNIK UND WIRTSCH (HTW) BERLIN (DE) | 2018-02-07 | — | — | EP | disclosed |
| WO-2017144099-A1 | AFFINITY LIGAND FOR THE PURIFICATION OF GLYCOSYLATED BIOMOLECULES | HOCHSCHULE FÜR TECHNIK UND WIRTSCHAFT (HTW) BERLIN (DE) | 2017-08-31 | — | — | WO | disclosed |
| WO-2016041844-A1 | PRODUCT PROTECTIVE CAPTURE AND ELUTION OF N-GLYCOSYLATED THERAPEUTIC GLYCOPROTEINS AND ENVELOPED VIRUSES | HOCHSCHULE FÜR TECHNIK UND WIRTSCHAFT (HTW) BERLIN (DE) | 2016-03-24 | — | — | WO | disclosed |
| EP-2998008-A1 | Product protective capture and elution of N-glycosylated therapeutic glycoproteins and enveloped viruses | Hochschule für Technik und Wirtschaft Berlin (DE) | 2016-03-23 | — | — | EP | disclosed |