SCHEMBL17600574

SCHEMBL17600574

CCO[Si](OCC)(OC(c1ccccc1)C(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.33
POLB P06746 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29002750 0.82 POLB (0.30) POLBLMNA
SCHEMBL27961555 0.78 NR1H2 (0.31)
SCHEMBL5875568 0.75 MAPK1 (0.34) KCNA5
SCHEMBL17600573 0.75 EDNRB (0.33) KCNA5
Chloromethane SCHEMBL27769943 0.74 LTA4H (0.34)
SCHEMBL29900 0.74 LTA4H (0.37)
SCHEMBL6036928 0.72 CA12 (0.36) POLBLMNA
SCHEMBL10495731 0.72 LTA4H (0.35)
Ammonia Solution, Strong SCHEMBL28965973 0.72 LTA4H (0.35)
SCHEMBL8415484 0.72 LTA4H (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109401710-A Dual-component silicane modified polyether seal glue and preparation method thereof 广州市白云化工实业有限公司 2019-03-01 CN disclosed
EP-3000804-B1 TRIPHENYLAMINE DERIVATIVE AND USE THEREFOR NISSAN CHEMICAL IND LTD (JP) 2018-04-25 EP disclosed
US-9780309-B2 Triphenylamine derivative and use therefor NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-10-03 US disclosed
EP-3000804-A1 TRIPHENYLAMINE DERIVATIVE AND USE THEREFOR Nissan Chemical Industries, Ltd. (JP) 2016-03-30 EP disclosed
US-20160087220-A1 TRIPHENYLAMINE DERIVATIVE AND USE THEREFOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160087220-A1 TRIPHENYLAMINE DERIVATIVE AND USE THEREFOR SLC7A1, SLC7A5, SLC7A11 KCNA5 1823/4885POLB 2236/4885LMNA 3590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.