Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360593 | 0.98 | TSHR (0.46) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| SCHEMBL2507036 | 0.93 | TSHR (0.42) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| SCHEMBL29354050 | 0.93 | TSHR (0.42) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL30943478 | 0.92 | TSHR (0.41) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| SCHEMBL27808614 | 0.92 | TSHR (0.41) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| SCHEMBL8623356 | 0.92 | TSHR (0.41) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| Phosphine SCHEMBL28247442 | 0.92 | TSHR (0.41) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| SCHEMBL3679296 | 0.90 | TSHR (0.40) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| Phosphoric Acid SCHEMBL5102243 | 0.90 | TSHR (0.40) | TSHRNPSR1RXFP1KMT2AMAPK1 | |
| Phosphoric Acid SCHEMBL20981646 | 0.90 | TSHR (0.40) | TSHRNPSR1RXFP1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572377-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220395510-A1 | Nucleotide Analogs | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS, OFFICE OF THE GENERAL COUNSEL (024) | 2022-12-15 | — | — | US | disclosed |
| US-11344555-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-31 | — | — | US | disclosed |
| EP-3194411-B1 | NUCLEOTIDE ANALOGS | UNIV CALIFORNIA (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20220072004-A1 | Nucleotide Analogs | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2022-03-10 | — | — | US | disclosed |
| EP-3350191-B9 | NUCLEOTIDE ANALOGS | UNIV CALIFORNIA (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-3875462-A1 | NUCLEOTIDE ANALOGS | The Regents of The University of California (US) | 2021-09-08 | — | — | EP | disclosed |
| US-20210246153-A1 | Nucleotide Analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-08-12 | — | — | US | disclosed |
| US-11014950-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-05-25 | — | — | US | disclosed |
| EP-3350191-B1 | NUCLEOTIDE ANALOGS | UNIV CALIFORNIA (US) | 2021-05-12 | — | — | EP | disclosed |
| US-20180362561-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-12-20 | — | — | US | disclosed |
| EP-3350191-A1 | NUCLEOTIDE ANALOGS | The Regents of the University of California (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20180015095-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-01-18 | — | — | US | disclosed |
| US-9801884-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-10-31 | — | — | US | disclosed |
| EP-3194411-A1 | NUCLEOTIDE ANALOGS | The Regents of the University of California (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2017048956-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-23 | — | — | WO | disclosed |
| US-20170037068-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-09 | — | — | US | disclosed |
| US-9493493-B2 | Nucleotide analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-15 | — | — | US | disclosed |
| WO-2016044281-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-24 | — | — | WO | disclosed |
| US-20160083407-A1 | NUCLEOTIDE ANALOGS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362561-A1 | NUCLEOTIDE ANALOGS | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-11572377-B2 | Nucleotide analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20180015095-A1 | NUCLEOTIDE ANALOGS | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-11014950-B2 | Nucleotide analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20220395510-A1 | Nucleotide Analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20220072004-A1 | Nucleotide Analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20160083407-A1 | NUCLEOTIDE ANALOGS | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-11344555-B2 | Nucleotide analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20170037068-A1 | NUCLEOTIDE ANALOGS | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
| US-20210246153-A1 | Nucleotide Analogs | NUDT1, DUT, DPYD | TSHR 3939/4885NPSR1 3809/4885RXFP1 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.