Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16179123 | 1.00 | GAA (0.62) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL30047147 | 1.00 | GAA (0.62) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL3849710 | 0.81 | SMN1; SMN2 (0.72) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL3849713 | 0.81 | SMN1; SMN2 (0.72) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL3847811 | 0.81 | SMN1; SMN2 (0.52) | GAAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3847809 | 0.81 | SMN1; SMN2 (0.52) | GAAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1110091 | 0.79 | KMT2A (0.62) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL30770327 | 0.76 | CES2 (0.66) | GAAKMT2AMEN1HTTGLO1 | |
| SCHEMBL9062780 | 0.76 | CES2 (0.66) | GAAKMT2AMEN1HTTGLO1 | |
| Malonic Acid Diethyl Ester SCHEMBL27871201 | 0.76 | MEN1 (0.58) | GAAKMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323066-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022221866-A1 | MEK INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |
| EP-2986611-B1 | CERTAIN PROTEIN KINASE INHIBITORS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2019-02-06 | — | — | EP | disclosed |
| US-10022374-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2018-07-17 | — | — | US | disclosed |
| US-20170105994-A1 | CERTAIN PROTEIN KINASE INHIBITORS | Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. (CN) | 2017-04-20 | — | — | US | disclosed |
| US-9556171-B2 | Certain protein kinase inhibitors | SHANGHAI FOCHON PHARMACEUTICAL CO., LTD. (CN) | 2017-01-31 | — | — | US | disclosed |
| US-20160083376-A1 | CERTAIN PROTEIN KINASE INHIBITORS | Shanghai Fosun Pharmaceutical Industrial Development Co., Ltd. (CN) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105994-A1 | CERTAIN PROTEIN KINASE INHIBITORS | PRKACA, PRKACB, PRKDC | GAA 2516/4885KMT2A 2635/4885MEN1 4052/4885 |
| US-20160083376-A1 | CERTAIN PROTEIN KINASE INHIBITORS | PRKACA, PRKACB, PRKDC | GAA 2516/4885KMT2A 2635/4885MEN1 4052/4885 |
| US-10022374-B2 | Certain protein kinase inhibitors | PRKACA, PRKACB, PRKDC | GAA 2516/4885KMT2A 2635/4885MEN1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.