Foramsulfuron

Foramsulfuron

SCHEMBL17604459

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2cc(NC=O)ccc2C(=O)N(C)C)n1.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.74
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.38
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
CA2 P00918 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
P2RY1 P47900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Foramsulfuron SCHEMBL19463617 0.87 CDK1 (0.67) CDK1KDM4ENPC1ALDH1A1GAA
Foramsulfuron SCHEMBL116874 0.86 CDK1 (1.00) CDK1GAASMN1; SMN2
Foramsulfuron SCHEMBL29419146 0.86 CDK1 (1.00) CDK1GAASMN1; SMN2
Foramsulfuron SCHEMBL2320828 0.85 CDK1 (0.98) CDK1GAASMN1; SMN2
Foramsulfuron SCHEMBL2973354 0.85 CDK1 (0.98) CDK1ALDH1A1GAASMN1; SMN2HTT
Foramsulfuron SCHEMBL15936497 0.84 CDK1 (0.94) CDK1GAASMN1; SMN2
SCHEMBL7060537 0.83 CDK1 (0.90) CDK1KDM4EALDH1A1GAASMN1; SMN2
Foramsulfuron SCHEMBL914629 0.82 CDK1 (0.64) CDK1GAA
Foramsulfuron SCHEMBL19463680 0.82 CDK1 (0.81) CDK1KDM4ENPC1ALDH1A1GAA
Foramsulfuron SCHEMBL19463951 0.81 CDK1 (0.79) CDK1KDM4EALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10448638-B2 Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors DOW AGROSCIENCES LLC (US) 2019-10-22 US disclosed
EP-3193598-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS Dow AgroSciences LLC (US) 2017-07-26 EP disclosed
US-20160135457-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS DOW AGROSCIENCES 2016-05-19 US disclosed
WO-2016044285-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS DOW AGROSCIENCES LLC (US) 2016-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160135457-A1 SYNERGISTIC WEED CONTROL FROM APPLICATIONS OF PYRIDINE CARBOXYLIC ACID HERBICIDES AND ALS INHIBITORS NOTUM, ABAT, SOD1 CDK1 2922/4885KDM4E 2442/4885NPC1 3727/4885
US-10448638-B2 Synergistic weed control from applications of pyridine carboxylic acid herbicides and ALS inhibitors NOTUM, ABAT, SOD1 CDK1 2922/4885KDM4E 2442/4885NPC1 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.