Foramsulfuron

Foramsulfuron

SCHEMBL914629

COC(=O)c1ccc(I)cc1S(=O)(=O)[N-]C(=O)Nc1nc(C)nc(OC)n1.COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2cc(NC=O)ccc2C(=O)N(C)C)n1.[Na+]

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Foramsulfuron. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.64
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Foramsulfuron SCHEMBL3230132 0.88 CDK1 (0.49) CDK1
SCHEMBL7643173 0.85 CDK1 (0.37) CDK1GAA
SCHEMBL924543 0.84 CDK1 (0.39) CDK1GAA
Foramsulfuron SCHEMBL17604459 0.82 CDK1 (0.74) CDK1GAA
SCHEMBL915255 0.82 CDK1 (0.38) CDK1GAA
Foramsulfuron SCHEMBL116874 0.80 CDK1 (1.00) CDK1GAA
Foramsulfuron SCHEMBL29419146 0.80 CDK1 (1.00) CDK1GAA
Foramsulfuron SCHEMBL15936497 0.79 CDK1 (0.94) CDK1GAA
Foramsulfuron SCHEMBL2973354 0.79 CDK1 (0.98) CDK1GAA
Foramsulfuron SCHEMBL2320828 0.79 CDK1 (0.98) CDK1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867946-B2 Liquid formulation BAYER CROPSCIENCE AG (DE) 2011-01-11 US disclosed
US-20060234868-A1 Liquid adjuvants BAYER CROPSCIENCE AG (DE) 2006-10-19 US disclosed
US-20060205596-A1 Liquid formulation BAYER CROPSCIENCE GMBH (DE) 2006-09-14 US disclosed
US-20050032647-A1 Mixture of herbically active material, solvent and sulfosuccinic acid compound BAYER CROPSCIENCE GMBH (DE) 2005-02-10 US disclosed
US-20050026786-A1 Oil suspension concentrate BAYER CROPSCIENCE GMBH (DE) 2005-02-03 US disclosed
US-20050026787-A1 Liquid formulation BAYER CROPSCIENCE GMBH (DE) 2005-02-03 US disclosed
US-6770594-B2 ONE OR MORE SURFACTANTS OTHER THAN SILICONE SURFACTANTS, AND ONE OR MORE HUMECTANTS. AVENTIS CROPSCIENCE (DE) 2004-08-03 US disclosed
US-20040116300-A1 Liquid adjuvants BAYER CROPSCIENCE GMBH (DE) 2004-06-17 US disclosed
US-20040013678-A1 Solid adjuvants BAYER CROPSCIENCE GMBH (DE) 2004-01-22 US disclosed
US-6573217-B2 Herbicidal compositions AVENTIS CROPSCIENCE GMBH (DE) 2003-06-03 US disclosed
US-20020072474-A1 Herbicidal compositions BAYER INTELLECTUAL PROPERTY GMBH (DE) 2002-06-13 US disclosed
US-20020058591-A1 Herbicidal compositions BAYER CROPSCIENCE GMBH (DE) 2002-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026786-A1 Oil suspension concentrate LIPA, BLVRB, DDT CDK1 3128/4885GAA 3705/4885
US-20050026787-A1 Liquid formulation SOD1, GLO1, MDM2 CDK1 1156/4885GAA 62/4885
US-20060234868-A1 Liquid adjuvants ACOX3, ACOX1, FFAR3 CDK1 496/4885GAA 4781/4885
US-20060205596-A1 Liquid formulation SOD1, GLO1, MDM2 CDK1 1156/4885GAA 62/4885
US-20050032647-A1 Mixture of herbically active material, solvent and sulfosuccinic acid compound STS, SCLY, SRM CDK1 2635/4885GAA 326/4885
US-20020072474-A1 Herbicidal compositions DDT, HDHD5, STS CDK1 2770/4885GAA 190/4885
US-20020058591-A1 Herbicidal compositions DDT, HDHD5, GLO1 CDK1 3053/4885GAA 78/4885
US-20040013678-A1 Solid adjuvants ACOX3, ACOX1, TLR1 CDK1 876/4885GAA 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.