Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CBFB | Q13951 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604570 | 0.82 | MAPT (0.38) | MAPTKDM4ELMNAPHF8KDM2A | |
| SCHEMBL17604506 | 0.81 | KDM4C (0.54) | KDM4EKDM2AKDM4CKDM5BKDM5A | |
| SCHEMBL16094975 | 0.81 | KDM4C (0.43) | MAPTKDM4ELMNAPHF8KDM2A | |
| SCHEMBL16095079 | 0.80 | ADORA2A (0.39) | MAPTKDM4ELMNAPHF8KDM2A | |
| SCHEMBL16095912 | 0.76 | KDM4C (0.61) | PHF8KDM2AKDM4CKDM5BKDM5A | |
| SCHEMBL27967673 | 0.74 | MAPT (0.43) | MAPTKDM4ELMNAMPOL3MBTL1 | |
| SCHEMBL2874146 | 0.74 | LMNA (0.43) | MAPTKDM4ELMNAMPOKDM5B | |
| SCHEMBL2873593 | 0.74 | MEN1 (0.48) | MAPTKDM4ELMNADAOL3MBTL1 | |
| SCHEMBL17604574 | 0.74 | PHF8 (0.37) | PHF8KDM4CKMT2A | |
| SCHEMBL2865485 | 0.73 | MAPT (0.41) | MAPTKDM4ELMNADAOMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |