Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792784 | 0.79 | NPY5R (0.45) | NPY5RKCNH2CCR1CCR5CCR8 | |
| SCHEMBL29500425 | 0.79 | NPY5R (0.45) | NPY5RKCNH2CCR1CCR5CCR8 | |
| SCHEMBL8299041 | 0.76 | IDO1 (0.53) | GRM5 | |
| SCHEMBL16095040 | 0.75 | NPY5R (0.36) | MAP3K14NPY5RKCNH2PRKD1PRKD2 | |
| SCHEMBL16094887 | 0.74 | TSHR (0.37) | MAP3K14NPY5RKCNH2GRM5 | |
| SCHEMBL16095484 | 0.74 | USP30 (0.38) | MAP3K14NPY5RKCNH2PRKD1PRKD2 | |
| SCHEMBL3440335 | 0.73 | GAA (0.51) | — | |
| SCHEMBL16034701 | 0.72 | NPY5R (0.40) | MAP3K14NPY5RKCNH2TRPV4METAP2 | |
| SCHEMBL16095540 | 0.72 | GRM5 (0.43) | GRM5 | |
| SCHEMBL17604545 | 0.72 | NPY5R (0.37) | MAP3K14NPY5RKCNH2TRPV4METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |