Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095040 | 0.78 | NPY5R (0.36) | USP30MAP3K14NPY5RKCNH2PRKD1 | |
| SCHEMBL16094449 | 0.77 | USP30 (0.36) | USP30MAP3K14NPY5RKCNH2SLC6A2 | |
| SCHEMBL16094887 | 0.75 | TSHR (0.37) | MAP3K14NPY5RKCNH2 | |
| SCHEMBL16095691 | 0.74 | FAAH (0.46) | PRKD1PRKD2METAP2METAP1 | |
| SCHEMBL16095001 | 0.74 | TAAR1 (0.44) | MAP3K14NPY5RKCNH2METAP2METAP1 | |
| SCHEMBL17604641 | 0.74 | MAP3K14 (0.39) | USP30MAP3K14NPY5RKCNH2PRKD1 | |
| SCHEMBL16095079 | 0.73 | ADORA2A (0.39) | NPY5RMETAP2METAP1 | |
| SCHEMBL16095540 | 0.72 | GRM5 (0.43) | — | |
| SCHEMBL16095066 | 0.72 | PHF8 (0.41) | — | |
| SCHEMBL16095191 | 0.72 | MAPK14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |