Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095540 | 0.87 | GRM5 (0.43) | VNN1HRH3GRM5LRRK2TDP2 | |
| SCHEMBL16095001 | 0.82 | TAAR1 (0.44) | IDH1HRH3NPY5RGRM5KCNH2 | |
| SCHEMBL16095079 | 0.81 | ADORA2A (0.39) | TSHRVNN1NPY5RGRM5LRRK2 | |
| SCHEMBL16095813 | 0.79 | PHF8 (0.39) | TSHRIDH1VNN1HRH3NPY5R | |
| SCHEMBL16095181 | 0.76 | KDM5B (0.44) | P2RX3 | |
| SCHEMBL16095040 | 0.76 | NPY5R (0.36) | NPY5RKCNH2MAP3K14 | |
| SCHEMBL16100266 | 0.76 | IDH1 (0.36) | TSHRIDH1MAOAMAOBVNN1 | |
| SCHEMBL16095066 | 0.75 | PHF8 (0.41) | TSHRVNN1GRM5 | |
| SCHEMBL16095102 | 0.75 | PHF8 (0.41) | NPY5RCTSS | |
| SCHEMBL16095484 | 0.75 | USP30 (0.38) | NPY5RKCNH2MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |