Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 11/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13814778 | 0.91 | CETP (0.37) | LMNAPTPN1AKT1PDPK1PHLPP1 | |
| SCHEMBL17607274 | 0.91 | LMNA (0.39) | LMNAPTPN1CDC25ACDC25BOPRM1 | |
| SCHEMBL17607217 | 0.91 | LMNA (0.39) | LMNAPTPN1CDC25ACDC25BOPRM1 | |
| SCHEMBL5545046 | 0.89 | CETP (0.39) | LMNAPTPN1AKT1PDPK1PHLPP1 | |
| SCHEMBL14012115 | 0.84 | — | — | |
| SCHEMBL7112064 | 0.81 | CETP (0.35) | LMNACETPCDC25ACDC25BOPRM1 | |
| SCHEMBL17761461 | 0.79 | LMNA (0.33) | LMNAPTPN1AKT1 | |
| SCHEMBL156086 | 0.76 | AKT1 (0.31) | AKT1PDPK1PHLPP1ILKCETP | |
| SCHEMBL10271778 | 0.75 | — | — | |
| SCHEMBL12590729 | 0.75 | CDC25A (0.32) | CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016043771-A9 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016043771-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-03-24 | — | — | WO | disclosed |