Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 2/20 | 0.30 |
| ▸ | CDC25B | P30305 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17607217 | 1.00 | LMNA (0.39) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17607221 | 0.91 | LMNA (0.36) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL7112064 | 0.90 | CETP (0.35) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17761461 | 0.84 | LMNA (0.33) | LMNAPTPN1 | |
| Oxirane SCHEMBL7121149 | 0.83 | CETP (0.32) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL13814778 | 0.82 | CETP (0.37) | LMNAPTPN1CDC25ACDC25B | |
| SCHEMBL17731285 | 0.81 | OPRM1 (0.36) | LMNAOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL14012115 | 0.80 | — | — | |
| SCHEMBL5545046 | 0.80 | CETP (0.39) | LMNAPTPN1CDC25ACDC25B | |
| SCHEMBL4302709 | 0.75 | LMNA (0.33) | LMNAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | claimed |
| WO-2016043771-A9 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-05-12 | — | — | WO | claimed |
| WO-2016043771-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-03-24 | — | — | WO | claimed |
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | disclosed |
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | CAI TINGWEI (US) | 2017-09-28 | — | — | US | disclosed |
| WO-2016043771-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2016-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275262-A1 | CYCLOPROPANE DERIVATIVES IN FLAVOR AND FRAGRANCE COMPOSITIONS | FAAH2, CNR1, TAS2R5 | LMNA 2619/4885OPRM1 233/4885OPRD1 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.