Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP14 | P31944 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | CASP12 | Q6UXS9 | 1/20 | 0.43 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17602080 | 0.90 | LTA4H (0.44) | LTA4HEGFRPTGS2CSF1RMEN1 | |
| SCHEMBL17602116 | 0.89 | LTA4H (0.43) | NPC1HTTRAB9ALTA4HPTGS2 | |
| SCHEMBL18984681 | 0.88 | RAB9A (0.54) | NPC1HTTRAB9ANPSR1RXFP1 | |
| SCHEMBL17609125 | 0.88 | MEN1 (0.45) | NPC1HTTRAB9ACASP3LTA4H | |
| SCHEMBL17602309 | 0.86 | MAPK1 (0.48) | HTTRAB9ALTA4HPTGS2PGR | |
| SCHEMBL17609138 | 0.84 | KDM4C (0.50) | LTA4HPTGS2LMNAKDM4EALDH1A1 | |
| SCHEMBL17602142 | 0.84 | KDM4C (0.47) | LTA4HPTGS2CSF1RKDM4EDRD1 | |
| SCHEMBL17602209 | 0.84 | KDM4C (0.44) | NPC1RAB9ALTA4HEGFRPDGFRB | |
| SCHEMBL17602210 | 0.84 | KAT2B (0.45) | NPC1RAB9ALTA4HPTGS2LMNA | |
| SCHEMBL17602207 | 0.84 | RAB9A (0.48) | NPC1HTTRAB9ANPSR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193601-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044429-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |