Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12592885 | 1.00 | ADORA2A (0.43) | ADORA2AADORA2BADORA1MCHR1PIK3CD | |
| SCHEMBL2929521 | 0.89 | ADORA2A (0.38) | ADORA2AADORA2BADORA1PIK3CD | |
| SCHEMBL1760945 | 0.84 | LMNA (0.47) | ADORA2AADORA2BADORA1 | |
| SCHEMBL12592858 | 0.83 | ADORA2B (0.51) | ADORA2AADORA2BADORA1TEAD1 | |
| SCHEMBL1760886 | 0.81 | ADORA2B (0.51) | ADORA2AADORA2BADORA1 | |
| SCHEMBL1761037 | 0.81 | ADORA2A (0.61) | ADORA2AADORA2BADORA1 | |
| SCHEMBL1761027 | 0.79 | ADORA2B (0.46) | ADORA2AADORA2BADORA1 | |
| SCHEMBL1760967 | 0.79 | PIK3CD (0.42) | ADORA2AADORA2BADORA1PIK3CDPIK3CA | |
| SCHEMBL12592897 | 0.79 | PIK3CD (0.42) | ADORA2AADORA2BADORA1PIK3CDPIK3CA | |
| SCHEMBL1761064 | 0.78 | ADORA2A (0.63) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947692-B2 | Substituted thiazolo[5,4-d]pyrimidine urea derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-05-24 | — | — | US | claimed |
| US-7947692-B2 | Substituted thiazolo[5,4-d]pyrimidine urea derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-05-24 | — | — | US | disclosed |