Ethylene Glycol

Ethylene Glycol

SCHEMBL1761129

CCCCCCCCCC(=O)OCC(C)(C)C.OCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.58
PAM P19021 2/20 0.53
LMNA P02545 4/20 0.51
KDM4E B2RXH2 1/20 0.51
DUSP3 P51452 1/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
MAPT P10636 2/20 0.50
TSHR P16473 1/20 0.50
PRKCA P17252 3/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
DNM1 Q05193 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL9815228 1.00 DGKA (0.58) DGKAPAMLMNAKDM4EDUSP3
Ethylene Glycol SCHEMBL1761137 1.00 DGKA (0.58) DGKAPAMLMNAKDM4EDUSP3
Ethylene Glycol SCHEMBL3649199 1.00 DGKA (0.58) DGKAPAMLMNAKDM4EDUSP3
Ethylene Glycol SCHEMBL9394363 1.00 DGKA (0.58) DGKAPAMLMNAKDM4EDUSP3
Ethylene Glycol SCHEMBL9390653 1.00 DGKA (0.58) DGKAPAMLMNAKDM4EDUSP3
Butane SCHEMBL1272560 0.96 DGKA (0.53) DGKAPAMLMNAKDM4EDUSP3
Ethylene Glycol SCHEMBL20270098 0.95 DGKA (0.52) DGKAPAMLMNAKDM4EDUSP3
SCHEMBL4624636 0.94 DGKA (0.64) DGKAPAMLMNAKDM4EDUSP3
SCHEMBL13073330 0.94 DGKA (0.64) DGKAPAMLMNAKDM4EDUSP3
SCHEMBL5709908 0.94 DGKA (0.64) DGKAPAMLMNAKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947635-B2 Hydrodynamic bearing device and spindle motor using the same PANASONIC CORPORATION (JP) 2011-05-24 US disclosed
US-20100029529-A1 Surfactant having chlorine-capturing ability and anti-discoloration ability and chemical formulation containing the same surfactant KIKUCHI RYUJI 2010-02-04 US disclosed
US-20090290821-A1 HYDRODYNAMIC BEARING DEVICE AND SPINDLE MOTOR USING THE SAME PANASONIC CORPORATION (JP) 2009-11-26 US disclosed
US-20070265181-A1 Surfactant having chlorine-capturing ability and anti-discoloration ability and chemical formulation containing the same surfactant KAWAKEN FINE CHEMICALS CO., LTD. (JP) 2007-11-15 US disclosed
US-20050282713-A1 Hydrodynamic bearing device and spindle motor using the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2005-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029529-A1 Surfactant having chlorine-capturing ability and anti-discoloration ability and chemical formulation containing the same surfactant KRT18, DSC1, DSG1 DGKA 1731/4885PAM 4064/4885LMNA 766/4885
US-20070265181-A1 Surfactant having chlorine-capturing ability and anti-discoloration ability and chemical formulation containing the same surfactant KRT18, DSC1, DSG1 DGKA 1731/4885PAM 4064/4885LMNA 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.