Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.65 |
| ▸ | THRA | P10827 | 8/20 | 0.65 |
| ▸ | PPARG | P37231 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | TTR | P02766 | 2/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | RXRA | P19793 | 2/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526276 | 1.00 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL19696721 | 0.93 | THRB (0.57) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL18557950 | 0.93 | THRB (0.57) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL13952217 | 0.93 | THRB (0.55) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL6995423 | 0.90 | THRB (0.65) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL13949755 | 0.90 | THRB (0.62) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL1525929 | 0.89 | THRB (0.57) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL12584422 | 0.88 | THRB (0.60) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL30745134 | 0.88 | THRB (0.60) | THRBTHRAPPARGMEN1KMT2A | |
| SCHEMBL30354491 | 0.87 | THRB (0.68) | THRBTHRAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289395-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof | NANOPHARMACEUTICALS LLC (US) | 2016-03-22 | — | — | US | disclosed |
| US-9289395-B2 | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof | NANOPHARMACEUTICALS LLC (US) | 2016-03-22 | — | — | US | disclosed |