SCHEMBL30354491

SCHEMBL30354491

O=C(O)[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)NI

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 12/20 0.68
THRA P10827 9/20 0.68
PPARG P37231 7/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
LMNA P02545 5/20 0.68
ADORA3 P0DMS8 3/20 0.68
PDE4D Q08499 3/20 0.68
HSD17B10 Q99714 3/20 0.68
RXRA P19793 3/20 0.68
TTR P02766 2/20 0.68
NR1I2 O75469 2/20 0.68
CYP1A2 P05177 2/20 0.68
HTR1A P08908 2/20 0.68
CYP2C9 P11712 2/20 0.68
HTR2B P41595 2/20 0.68
PGR P06401 2/20 0.68
NR3C1 P04150 1/20 0.68
TBXA2R P21731 1/20 0.68
NTSR1 P30989 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27988679 1.00 THRB (0.68) THRBTHRAPPARGMEN1KMT2A
SCHEMBL27940335 0.99 THRB (0.67) THRBTHRAPPARGMEN1KMT2A
SCHEMBL8201938 0.90 THRB (0.68) THRBTHRAPPARGMEN1KMT2A
SCHEMBL17612148 0.90 THRB (0.68) THRBTHRAPPARGMEN1KMT2A
SCHEMBL27988678 0.88 THRB (0.60) THRBTHRAPPARGMEN1KMT2A
SCHEMBL28258110 0.88 THRB (0.70) THRBTHRAPPARGMEN1KMT2A
SCHEMBL12844205 0.88 THRB (0.67) THRBTHRAPPARGMEN1KMT2A
Hydrochloric Acid SCHEMBL11503377 0.88 THRB (0.67) THRBTHRAPPARGMEN1KMT2A
Hydrochloric Acid SCHEMBL11503379 0.88 THRB (0.67) THRBTHRAPPARGMEN1KMT2A
SCHEMBL17612149 0.87 THRB (0.65) THRBTHRAPPARGMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113260385-B Methods of treating cancer with anti-VEGF antibody and anti-tissue factor antibody-drug conjugate combinations 展马博联合股份有限公司 2025-02-11 CN disclosed
CN-112203695-B Methods of treating cancer with combinations of platinum-based agents and anti-tissue factor antibody-drug conjugates 展马博联合股份有限公司 2024-11-01 CN disclosed
CN-112368020-B Methods of treating cancer with anti-PD-1 antibodies and anti-tissue factor antibody-drug conjugate combinations 展马博联合股份有限公司 2024-05-31 CN disclosed
CN-117859912-A Preparation method and application of probiotics capable of improving intestinal tract field planting efficiency 恩施德源硒材料工程科技有限公司 2024-04-12 CN disclosed
CN-114813988-B Method for simultaneously extracting and detecting thyroid hormone and steroid hormone in hair 东南大学 2023-12-29 CN disclosed
CN-113197075-B Processing method of asparagus rich in organic selenium 湖北国硒科技发展有限公司 2023-11-24 CN disclosed
CN-110612105-B Process for preparing carbamate sulfonic acid bile acid derivatives 英安塔制药有限公司 2023-05-02 CN disclosed